Megamind is a 2010 3D animated superhero comedy film produced by DreamWorks Animation and Red Hour Productions, and distributed by Paramount Pictures. The film was released in the United States in Digital 3D, IMAX 3D and 2D on November 5, 2010. It features the voices of Will Ferrell, Brad Pitt, Tina Fey, David Cross, and Jonah Hill. The film is directed by Tom McGrath.
Megamind (Will Ferrell), a super-intelligent alien, has constantly battled his nemesis Metro Man (Brad Pitt) since they both arrived on Earth as infants. Consistently losing to Metro Man, Megamind believes himself destined to be the villain. On the day that Metro City dedicates a museum to their protector, Megamind and his sidekick Minion (David Cross) kidnap reporter Roxanne (Tina Fey), and then lure Metro Man into a copper-lined room. To everyone's surprise, Metro Man is unable to escape, and appears to be killed when Megamind's death ray strikes him. Megamind revels in his victory, but shortly becomes depressed, his villainy having no meaning without anyone to stop him.
While attempting to destroy the museum, he disguises himself as its curator, Bernard (Ben Stiller) to hide himself from Roxanne. As he talks with her, Megamind is inspired to create a superhero by injecting a worthy target with a serum fashioned from Metro Man's DNA, granting them Metro Man's super-abilities. As Megamind is selecting his target, Roxanne sneaks into Megamind's lair; in the resulting chaos, Megamind accidentally fires the serum into Hal, Roxanne's cameraman. Taking advantage of the gullible Hal, Megamind appears to the transformed human as his "space dad", grooming Hal into the superhero Tighten (Hal's misunderstanding of Megamind's original name "Titan") and preparing him to fight Megamind in the coming days. Meanwhile, Megamind has become attracted to Roxanne, and continues to date her using his Bernard disguise. Tighten, also infatuated with Roxanne, becomes jealous of Bernard, while Minion, seeing Megamind losing interest in villainy, angrily leaves him. On a dinner date, Megamind's disguise falters, leading Roxanne to dump him. Megamind, heartbroken, returns to his lair and vows to fight Tighten the next day.
Megamind becomes impatient waiting for Tighten and seeks him out, finding the superhero has used his powers for nefarious purposes. Megamind taunts Tighten into fighting him by revealing his Bernard and space dad disguises. In the midst of the fight, Megamind tries to capture Tighten in a copper-lined trap, and is shocked to find it fails to work. The villain flees, leaving the city to celebrate Tighten's victory, until the "hero" reveals that he is taking over the city, and goes on a destructive rampage. Megamind returns to Roxanne, apologizing and convincing her to lead him to Metro Man's secret headquarters where they might find another way to stop Tighten. They are surprised to find Metro Man still alive, secluded in his headquarters. Metro Man reveals he had become tired of fighting Megamind, and had an epiphany that day, faking his own death to pursue his career as a musician. Without any new leads, Roxanne tries to convince Megamind to fight Tighten as the city's hero, but Megamind feels he is destined to always be the villain, and turns himself back in to prison.
Later, Tighten captures Roxanne and secures her to the top of Metro Tower, threatening to kill her if Megamind does not fight him. Seeing Roxanne in danger, Megamind pleads to the warden for his release, apologizing for all the wrongs he committed before. To the villain's surprise, Minion has disguised himself as the warden, and accepts Megamind's apology, and the two take off to the city. They use an elaborate ruse, Minion disguising himself as Megamind to lure Tighten from the tower, while Megamind disguises himself as Metro Man to save Roxanne and verbally berate Tighten. Tighten is temporarily bested, and told by "Metro Man" to leave "metrosity" (Megamind's distinctive mispronounciation of "Metro City"), but the defeated hero shortly returns, seeing through Megamind's disguise. Megamind is forced to run from Tighten's wrath, until Roxanne discovers where Megamind left his invisible car and the tool to extract the superhero serum from Tighten. Megamind successfully retrieves the device and uses it on Tighten, reverting him to Hal. The city cheers for its new hero, a role that Megamind realizes he is capable of choosing himself.
In the aftermath, the former Metro Man museum is rededicated to Megamind, who is slowly coming around to being the hero. He and Roxanne have developed a relationship, and hidden in the crowds, a concealed Metro Man gives Megamind his congratulations.